We Finally Get a Vaxxed v. Unvaxxed Study, Vaccinated Primates Have Brain Changes Seen In Autism

We finally get a vaccinated v. unvaccinated study. No... no actual children yet, but infant rhesus macaque monkeys.



And no wonder main stream medicine doesn't want vaccine studies with an actual baseline (completely unvaccinated), because the results are dramatic.

The infant primates vaccinated according to the US vaccine schedule (equivalent to their size/development rate, pre 2002 shots WITH full doses of mercury) showed the same brain changes found in children with autism. The amygdala, the fear and anxiety center, did not mature properly in the vaccinated group, and those differences did not appear until AFTER the 12 month vaccines were given.

The abstract:

Influence of pediatric vaccines on amygdala growth and opioid
ligand binding in rhesus macaque infants: A pilot study

Acta Neurobiol Exp 2010, 70: 147–164
©2010 by Polish Neuroscience Society - PTBUN, Nencki Institute of Experimental Biology

Laura Hewitson1,2,*, Brian J. Lopresti3, Carol Stott4, N. Scott Mason3 and Jaime Tomko1

1Department of Obstetrics and Gynecology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA;
2Thoughtful House Center for Children, Austin, TX, USA; 3Department of Radiology, University of Pittsburgh School of
Medicine, Pittsburgh, PA, USA; 4Independent Chartered Scientist, Cambridge, UK;
*Email: lch1@pitt.edu

This longitudinal, case-control pilot study examined amygdala growth in rhesus macaque infants receiving the complete US childhood vaccine schedule (1994-1999). Longitudinal structural and functional neuroimaging was undertaken to examine central effects of the vaccine regimen on the developing brain. Vaccine-exposed and saline-injected control infants underwent MRI and PET imaging at approximately 4 and 6 months of age, representing two specific timeframes within the vaccination schedule. Volumetric analyses showed that exposed animals did not undergo the maturational changes over time in amygdala volume that was observed in unexposed animals. After controlling for left amygdala volume, the binding of the opioid antagonist [11C]diprenorphine (DPN) in exposed animals remained relatively constant over time, compared with unexposed animals, in which a significant decrease in [11C]DPN binding occurred. These results suggest that maturational changes in amygdala volume and the binding capacity of [11C]DPN in the amygdala was significantly altered in infant macaques receiving the vaccine schedule. The macaque infant is a relevant animal model in which to investigate specific environmental exposures and structural/functional neuroimaging during neurodevelopment.

Key Words: rhesus macaques, Macaca mulatta, non-human primates, animal model, neuroimaging, PET, MRI, amygdala, opioids, ethyl mercury, thimerosal, neurotoxicity

The full paper: Hewitson et. al.

The editorial written by the editor of the journal, who says:

An alarming finding is reported by Hewitson and coworkers showing that, in infant monkeys that were immunized, the amygdala does not show the normal pattern of maturation but is hypertrophied. Although these are only preliminary data, given the well-known role of the amygdala in generation of fear and other negative emotions, they support the possibility that there is a link between early immunization and the etiology of autism.

Mark Blaxill and Dan Olmsted's discussion of the paper: New Study Shows Vaccines Cause Brain Changes Found in Autism

It should be noted that in the spring of 2008, The American Academy of Pediatrics was informed of this study. At the conclusion of the DAN conference in Cherry Hill, NJ in April of 2008, Dr. Jerry Kartzinel personally discussed it with Dr. Louis Cooper who was there representing the AAP. Cooper skirted the issue, acting as if he was concerned with the cost of the study, and Kartzinel replied that the study was fully funded and underway. Cooper was clearly not comfortable with the discussion of the study, and changed the subject. In their discussion of what Cooper had seen at the conference and how to proceed with some sort of partnership between ARI and AAP, Cooper had already stated to Kartzinel:

"I’m concerned about immunization policy and how you protect immunization."

To my knowledge, AAP never got back to anyone on their input into, or involvement with, this primate study. Note that the study was not published by Pediatrics, where it belongs, as it is AAP's journal and AAP is Pharma's main vaccine distributor. I am sure they want this buried as deep as is possible.

I am interested to see what AAP's public comment will be on this. If there is one.

AAP's (@ameracadpeds)twitter page can be found here: http://twitter.com/ameracadpeds

Feel free to call this post to their attention.

Congressional Briefing by Maloney on Vaxxed v. Unvaxxed Bill

Call your Senators and Representatives offices and ask them to attend:

Rep. Maloney and Rep. Smith To Host A Second Autism Congressional Briefing An Update On Federal Autism Research And Treatment Initiatives

PLEASE CONTACT YOUR US SENATORS (HERE) AND MEMBERS OF CONGRESS (HERE) AND URGE THEM TO ATTEND OR SEND A STAFF MEMBER TO THIS IMPORTANT AUTISM-VACCINE BRIEFING ON CAPITOL HILL

Friday, July 17 at 9:30 AM
210 Cannon House Office Building
Independence Avenue, Washington, DC.

FREE AND OPEN TO THE PUBLIC

Rep. Carolyn Maloney (D-NY) and Rep. Christopher Smith (R-NJ) is hosting a special briefing for Members of Congress and their Staff to discuss issues related to autism research and treatment. We hope that you will attend the briefing to learn about the changing dynamics of the autism debate, as you will find many in government and science believe this debate is far from settled.

David Kirby, investigative journalist and author of The New York Times bestseller Evidence of Harm, Mercury in Vaccines and the Autism Epidemic – A Medical Controversy, will inform Members and their staff about developments regarding environmental factors in autism and the “Seven Studies to Watch” – Plus, changing ASD demographics post-thimerosal reduction. Mr. Kirby will also be joined by Mark Blaxill, Editor-at-Large of Age of Autism, Director of the Coalition for SAFE MINDS and co-author of a forthcoming book on the roots of the autism epidemic, who will address the policy and public health implications of the autism crisis.
Among the issues to be discussed are:

• The unanimous endorsement by the National Vaccine Advisory Committee to look at the feasibility of a large vaccinated-unvaccinated study, with autism as an outcome.
• 
  
• The NVAC endorsement of three other vaccine-autism investigations, including children with mitochondrial dysfunction, children with regressive autism, and vaccine injury as a risk factor for ASD.
• 
  
• Recent Vaccine Court decisions finding the MMR and Hep B vaccines caused injuries that led to autism and MS.
• 
  
• The NIH Early Autism Risk Longitudinal Investigations EARLI study and the HHS/EPA National Children’s Study, both of which are looking at vaccination and mercury exposures, with autism as a possible outcome.
• 
  
• The CDC’s Centers for Autism and Developmental Disabilities Research and Epidemiology (CADDRE) Network, whose five-year goal includes studying "specific mercury exposures, including any vaccine use by the mother during pregnancy and the child's vaccine exposures after birth.”
• 
  
• Cleveland Clinic – A recent article in PLoS Online by authors from the Cleveland Clinic, Harvard and Johns Hopkins University reported that, "Large, population-based studies will be needed to identify a possible relationship of vaccination with autistic regression in persons with mitochondrial dysfunction.”
• 
  
• Recent statements by Federal health officials such as Dr. Duane Alexander, Director of the Eunice Kennedy Shriver Institute of Child Health and Human Development (NICHD), who said it was “legitimate to ask” whether vaccines can trigger autism, and Dr. Anthony Fauci, Director of NIAID, who said in a US News and World report article, “we may want to screen everyone prior to vaccination (for) undetectable diseases like a subclinical mitochondrial disorder."
• 
  
• The U.C. Davis M.I.N.D. Institute study which found, that the seven- to eight-fold increase in the number children born in California with autism since 1990 cannot be explained by either changes in how the condition is diagnosed or counted — and the trend shows no sign of abating. This as young adults begin to flood the social services system
• 
  
• Reports of reduced Autism Spectrum Disorder (ASD) severity among the youngest children, following reduction of thimerosal in childhood vaccines.

Please contact your elected representatives and urge them to attend.
A RUNNING TALLY OF CONGRESSIONAL RSVPS WILL BE KEPT AT WWW.AGEOFAUTISM.COM,
IF YOU RECEIVE ANY REPLY FROM LAWMAKERS IN YOUR STATE, PLEASE FORWARD THAT INFORMATION TO kirbylecture@gmail.com

Maloney Vaxxed v. Unvaxxed Study Reintroduced

Call your representative and ask for support for HR 3069.

FOR IMMEDIATE RELEASE: June 28, 2009
CONTACT: .
Jon Houston, Maloney, (202) 225-7944

Jeff Sagnip, Smith, (202) 225-3765

Legislation Introduced to Require First Comparative

Study of Vaccinated vs. Unvaccinated Populations

WASHINGTON, DC – Reps. Carolyn Maloney (D-NY) and Christopher Smith (R-NJ) have introduced the “Comprehensive Comparative Study of Vaccinated and Unvaccinated Populations Act of 2009,” HR 3069, legislation that would require the Secretary of Health and Human Services to conduct a comprehensive, peer-reviewed, comparative study of vaccinated and unvaccinated populations, which has never before been completed.

“Vaccines have been instrumental in reducing the incidence of many once-common diseases, but we owe it to parents and children to study and resolve the questions that have arisen over the possible link between vaccines and neurological disorders,” said Maloney. “What is ultimately needed to resolve this issue is a comprehensive national study comparing outcomes between vaccinated and unvaccinated children. As the most scientifically advanced country in the world, we should be jumping at the chance to resolve the questions that have been raised. Parents deserve answers, and children deserve no less than absolute certainty and safety.”

“Vaccines have been a truly revolutionary contribution to global public health that I have strongly supported. At the same time, it would be unconscionable if we did not fully investigate every aspect of vaccine safety, including varying vaccines schedules, to ensure that individuals were not being exposed to unnecessary risks,” said Smith. “This study would explore critical questions about our children’s health. Only a comprehensive, national examination of data that contrasts vaccinated children to unvaccinated children will answer some of the questions many if not all parents have about the safety of the vaccines we give our children. Congresswoman Maloney and I feel strongly that this will add greatly to the body of knowledge for the healthcare community and the public.”

Other original cosponsors of the bill include Rep. Bart Gordon (D-TN), Chair of the House Science and Technology Committee, and Reps. Dan Burton (R-IN), Patrick Kennedy (D-RI), Jim Langevin (D-RI), Virginia Brown-Waite (R-FL), and Grace Napolitano (D-CA).

Background: Maloney and Smith have also introduced legislation (H.R. 2618) that would improve the current system for vaccine safety monitoring in this country by assigning responsibility for the nation’s vaccine safety to an independent agency within the Department of Health and Human Services; and another (H.R. 2617) that puts in statute definite timelines for the elimination of mercury from vaccines.

Maloney introduced similar legislation in the 110th Congress. Click here for more information.

Dan Olmsted Is Back

... and calling out the CDC's shenanigans on The Rescue Post.

If you have not already made The Rescue Post a part of your regular blog reading, time to grab the feed.

America, Meet Your Unvaccinated Kids

The Rescue Post is calling your attention again to the first study of vaccinated v. unvaccinated children and their risk for disorders like Autism, ADHD, Asthma and the like. The study was released in June and ignored by the mainstream media.

Those of you who are here because you saw Jenny MCCarthy, our new autism spokes mom, on the tele should take a look at the survey.

If you vaccinated your son, they have a %155 higher chance of having a neurological disorder had you chosen not to vaccinate.

The question that we have been screaming at the CDC for years, and they will not answer, is this:

Are we trading curable communicable diseases for incurable neurological diseases by over vaccinating our children, and by not screening to see which children cannot tolerate vaccination.

Handley: America, Meet Our Unvaccinated Kids

J.B. Handley introduces America to its unvaccinated children today on the Rescue Post.

In this post he offered the data from the Generation Rescue Survey released today that shows that vaccinated children have a 2.5 times higher risk of developing a neurodevelopmental disorder like autism as compared to non vaccinated children.

America, Meet Our Unvaccinated Kids
By J.B. Handley

For the first time ever, we know something about them that may help our kids.

Yup, they live right down the street from you, they are 5.6% of the population, and they have less asthma, less ADHD, and less autism than our kids seem to have. At least according to our survey.

Do we expect you to believe us? Not really. Not if you’re a member of the mainstream media or the mainstream medical establishment. But, we really hope you will look at our data. Because today, unlike the CDC, we are making all of our data public simultaneously with the release of our survey. Crunch away, and decide for yourself.

We followed a very straightforward process, so anyone can retrace our steps. We told a market research firm what we wanted to know. They designed a questionnaire they felt would get us an answer. We approved the questionnaire. They ran the survey and sent us the data, which you can now access. Decide for yourself.

Some of the numbers really jump out, particularly amongst the boys. A “Risk Ratio” is a way to compare prevalence, so that if 10% of vax kids and 5% of unvax kids have ADHD, the Risk Ratio is 2.0, or a 100% difference. Risk Ratios above 2.0 tend to be allowed in a court of law to show correlation. We found many Risk Ratios well in excess of 2.0, and some higher than 4.0, the equivalent of a 300% difference. Decide for yourself.

Have we proved anything today? Yes and no. We’ve proved that unvaccinated kids are easy to find, and that a straightforward survey yielded some disturbing results. What we haven’t done is design a study with enough scale and controls to be published in a first-tier, peer-reviewed journal. But, we’ve certainly highlighted the screaming need for such a study to happen.

So, now what?

Everyone should write Dan Olmsted and thank him for his Age of Autism series from UPI. He’s the one who asked about unvaccinated kids first, and asked it loudest. He even asked Julie Gerberding, CDC Director. He just kept on asking it until we got so tired thinking about what an obvious question it was that we did something about it.

Our data should be scrutinized, analyzed, challenged, and debated by any and everyone in the autism community who cares to do so. (If you want a copy of the Excel spreadsheet with the primary data in it, email me and I will send it to you.)

Everyone and their grandmother needs to cajole their Congressperson to jump on the bandwagon and support Carolyn Maloney's Bill to study unvaccinated children.


This incredibly brave Congresswoman from New York said in a press release yesterday: “What is ultimately needed to resolve this issue one way or the other is a comprehensive national study comparing outcomes between vaccinated and unvaccinated children. As the most scientifically advanced country in the world, we should be jumping at the chance to conduct a comprehensive national study to resolve the questions that have been raised. Parents deserve answers, and children deserve no less than absolutely certainty and safety.”

The autism community should pull together and fund our own independent study, in addition to the Maloney bill, to gather as much data as quickly as possible. Autism Speaks, with the biggest war chest, should take this opportunity to fund or lead the funding for such a study, and help put this issue to rest once and for all. It would be a great opportunity for them to repair a badly burned bridge with many of us, and I hope they jump at the chance. The study must be run by researchers who have no history in this fight, on either side of the argument, and it must have the scale and controls to achieve wide acceptance through journal publication.


As for me, nothing much changes. My son is getting better, and we think the road map drawn by considering him “vaccine injured” is why. Knowing cause is so incredibly important to figuring out how to help and treat our kids, and I’m grateful for the pioneers who have been demanding answers for years. My wife and I hope, in some small way, that this survey moves things forward, and creates a deafening demand from parents for more answers. Now.

J.B. Handley is co-founder of Generation Rescue.